I always try to use new pinch lock nuts and check to be sure the bolts are the correct type. I try not to use nyloc nuts as these tend to back off. I also never Loctite them, because if they are at the proper torque, all the hardware is correct, and everything is in balance, the nuts shouldn’t come loose. I must’ve replaced hundreds of giubos in my life as a mechanic, on all sorts of BMWs, Mercedes, etc., and never had one nut back off, unless the giubo failed for other reasons.